Trienamines derived from 5-substituted furfurals: remote ε-functionalization of 2,4-dienals.
نویسندگان
چکیده
The selective ε-functionalization of 5-substituted furfurals via trienamine intermediates is reported herein. This methodology was successfully applied to several 5-substituted furfurals with different amines via formation of a trienamine through the furan ring. The rationalized reaction mechanism involves the addition of the trienamine intermediate to its corresponding iminium-ion producing new furan-containing scaffolds.
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ورودعنوان ژورنال:
- Organic & biomolecular chemistry
دوره 12 46 شماره
صفحات -
تاریخ انتشار 2014